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Olive oil and butter do not vary substantially in calorie count. One tablespoon of olive oil comprises approximately 120 calories, while 1 tbsp. of butter contains about 100 calories. However, there are differences in the nutritional properties in between olive oil and butter. Various research shows which a diet regime which contains olive oil, has important preventive wellness benefits, such as minimizing the hazards for heart disease. An additional critical distinguishing is which olive oil, which is a plant-based food, has no cholesterol while butter does.